Beilstein J. Org. Chem.2020,16, 2100–2107, doi:10.3762/bjoc.16.177
-cho, Chikusa-ku, Nagoya, Aichi, Japan 10.3762/bjoc.16.177 Abstract Two new azaphilones, namely muyocopronones A (1) and B (2), were isolated from the cultures of an endophytic fungus Muyocopronlaterale ECN279. Their structures were elucidated by extensive spectroscopic analysis. Their absolute
fungus; modified Mosher’s method; Muyocopronlaterale; polyketides; Introduction
Azaphilones, which are a class of fungal polyketides with diverse structures, have received growing attention due to their various biological activities, such as the inhibition of some protein–protein interactions [1][2
fungal metabolites produced by Muyocopron spp. Thus, as part of our research into the natural products produced by plant-associated fungi [13][14][15], we isolated two new azaphilones from the cultures of an endophytic fungus, namely Muyocopronlaterale ECN279. Herein, the isolation, structural